Endocrine Abstracts

Introduction: The development of malignancies in patients with Primary Hyperparathyroidism (PHP) occurs in the context of Multiple Endocrine Neoplasia (MEN) Syndrome. The association of PTH levels with cancer in patients with sporadic PHP has not been clarified. The aim of this study was to investigate whether PTH levels are related to the presence of thyroid cancer (TH) or other types of cancer in patients with PHP.Methods: We included patients with bio...

Introduction: Vitamin D is essential for calcium metabolism and is involved in bone turnover. The purpose of this study was to examine vitamin D status and its relation with bone metabolism in adult patients with T1DM.Methods/Design: We studied 118 patients with T1DM (Group-D) (mean age: 35.4+10.3 years) and 94 healthy controls (Group-C) matched for age, sex and body mass index (BMI). In both groups HbA1c, 25(OH)Vitamin D (Vit-D), serum calcium (Ca), pho...

Introduction: Most thyroid neoplasms arise from follicular cells and are well differentiated. We present an interesting case of a rare first manifestation of Papillary Thyroid Carcinoma (PTC) as a cervical cystic mass, as well as the therapeutic approach.Material-method: A 29 year-old-male, without personal or family history for PTC and no history of neck radiation referred to our department because of a slow growing right lateral cervical mass in the la...

Introduction: TSI (Thyroid Stimulating Immunoglobulin) antibodies are a form of immunoglobulin G (IgG) that can bind to thyrotropin receptors on the thyroid gland causing over-production of thyroid hormones and hyperthyroidism. The presence of positive TSI is considered pathognomonic for Graves’ disease. Although the association between Graves’ disease and thyroid cancer (TC) has been reported in previous studies, the association between the levels of TSI antibodies ...

Introduction: Although computed tomography (CT) is the best mean to identify adrenal neoplasms there is still controversy of the concordance of the estimated radiological and histological size of the lesion. Since the size of adrenal tumours is a major criterion for surgical excision, we investigated whether recent and more sophisticated imaging techniques, can more accurately predict tumor’s size.Methods: We have retrospectively analyzed a series o...

Background and aims: Gestational diabetes (GD) is closely related to unbalanced zinc (Zn) and cooper (Cu) serum levels. The aim of this study was to investigate serum zinc and cooper levels in relation to the metabolic profile, and the impact on fetal development in a cohort of gestational diabetes GD(N) neonates and their mothers GD(M) compared to normal pregnancies.Material and Methods: Prospective controlled study in a tertiary Academic medical center...

Background: Intestinal metaplasia (IM) of the gastric mucosa is a relatively frequent precancerous lesion. The aim of the study was to assess the prevalence and the kind of IM and also to find parameters that could predict the presence of IM in gastric neuroendocrine neoplasms type 1 (GNEN1).Methods: Fifty-nine (45 females) patients with GNEN1 were retrospectively studied. All patients included in the study had positive parietal-cell antibodies. All pati...

Objective: To define the prevalence of Diabetic Peripheral Neuropathy (DPN), painful diabetic neuropathy (PDN) and the at risk diabetic foot in 2 out of the 3 National Diabetes Centres in Qatar.Methods: 712 people with Type-1 & Type-2 diabetes recruited from Alwakra Hospital and Hamad General Hospital underwent assessment for DPN & PDN using the Neurothesiometer and the DN4 questionnaire, respectively.Results: The average a...

Introduction: Type 2 diabetes mellitus (T2DM) affects bone metabolism, but its relation with bone mineral density (BMD) remains controversial. It is also known that T2DM is associated with hypogonadism in males. Male hypogonadism can also affect BMD. Thus the aim of this study was to evaluate BMD in male patients with T2DM with and without hypogonadism.Methods/design: Hypogonadism was defined as serum free Testosterone (fT) value <5 ng/dl or 5–9...

Background: Anabolic androgenic steroids (AAS) are widely used to improve performance and/or enhance appearance. The aim of this study was to assess the impact of AAS on the reproductive system of athletes.Methods: An electronic literature search was conducted, using the databases MEDLINE, CENTRAL, Scopus and Google Scholar. Studies including AAS use in any type, dose, form or duration of intake were included in the review. Main outcomes were AAS effects...